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Hypoxia-activated 2-nitroimidazole-brusatol carbonate prodrugs for enhanced...

Publication date: Available online 28 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Jichong Li, Xuelan Ma, Zijian Liu, Xinyu Chang, Yifan Wei, Ning Ma, Xiaoling Liu, Xuan Zhang,...

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Criteria-guided selection of alternative zinc-binding groups of HDAC3...

Publication date: Available online 25 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Thabo Brighton Makgoba, Samuel Egieyeh, Erika Kapp, Jacques Joubert

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Rivastigmine-centered molecular hybridization strategies for multi-targeted...

Publication date: Available online 25 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Nitin Kumar, Virendra Kumar Kushwaha, Gourav Singh, Smriti Ojha, Alok Kumar Dash, Gauri Shankar

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Design, synthesis and biological evaluation of a series of new, potent FLT3...

Publication date: December 2026Source: Bioorganic & Medicinal Chemistry, Volume 143Author(s): Licheng Zhou, Yinglong Chen, Jiahe Li, Yayuan Yang, Wenyan Liu, Yingfan Liu, Bohai Fan, Yang Zhou,...

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Design, synthesis, and biological evaluation of novel dihydropyrimidinone...

Publication date: Available online 23 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Marian N. Gerges, Ahmed A. Noser, Eman G. Ibrahim, Thoria Diab

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Redirecting MurD inhibitor preference toward MurD2 through glutamate...

Publication date: Available online 15 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Zhuang Qian, Yu Nakashima, Tohru Dairi, Hiroyuki Morita

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Design, synthesis, biological and computational evaluation of Thieno[3,2-d]...

Publication date: Available online 12 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Poowadon Fukasem, Kittitat Jaengwang, Duangkamol Gleeson, Robert G. Britton, Kiattawee...

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An in vitro comparative study of cefiderocol, siderophore-aztreonam and...

Publication date: Available online 11 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Rui Liu, Patricia A. Miller, Marvin J. Miller

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Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1...

Publication date: December 2026Source: Bioorganic & Medicinal Chemistry, Volume 143Author(s): Ajay L. Chandgude, Giovanni Loriga, Andrea Beccu, Fabio Arturo Iannotti, Ester Pagano, Raffaele...

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Graphical abstract TOC

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Graphical abstract TOC

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Contents continued

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Editorial Board

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Structural optimization of...

Publication date: Available online 6 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Hiroshi Inami, Junko Watanabe, Naohiro Aoyama, Hiroyuki Usuda, Tsuyoshi Mizutani, Hisashi...

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Design, synthesis and evaluation of fluorinated CYP1B1 inhibitors based on a...

Publication date: Available online 2 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Meixian Yang, Xin Liu, Xin Wei, Dachuan Qiu, Weijuan Chen, Jiajing Cai

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Discovery of SARS-CoV-2 PLpro covalent inhibitors enabled by a novel...

Publication date: Available online 29 August 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Divakar Indukuri, Jazmin Galván Achi, Boopathi Sownthirarajan, Malla Reddy Gannarapu, Omar Lozano...

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Design, synthesis, and biological evaluation of novel phenylindole...

Publication date: Available online 29 August 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Zhikun Yang, Yingjia Ding, Keren Xu, Jiajia Han, Junzhe Hu, Sherien M. Bakry, Yi Hua, Hong Wang

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A novel ring-opened ebselen scaffold with potent anti-angiogenic activity...

Publication date: Available online 29 August 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Shuxiao Feng, Zongluo Zhang, Xuan Zhong, Jiahao Chen, Kejia Ren, Yishuai Wu, Tianxin Ji, Tong Wu,...

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Evaluating the outputs of ARAE-based molecular generative model for synthetic...

Publication date: December 2026Source: Bioorganic & Medicinal Chemistry, Volume 143Author(s): Goutham Rajendran, Thanh-Hoang Nguyen-Vo, Hunter C. Murray, Robert A. Keyzers, Jordan A.J. McCone,...

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Functional mapping of the Trypanosoma cruzi serinome by fluorophosphonate...

Publication date: Available online 29 August 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Jaime A. Isern, María Gabriela Mediavilla, Exequiel O.J. Porta, Marcelo L. Merli, María Sol...

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