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Development of dihydroquinolizinone (DHQ)-based inhibitors for suppression of...

Publication date: Available online 7 October 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Han Yu, Zuo Yinglin, Jiang Zhidong, Liu Rong, Xu Honggui, Tang Lin, Liu Xinchang, Yan Guanghua,...

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Novel trans-stilbene-phytophenol conjugates as potent tubulin-targeting...

Publication date: Available online 6 October 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Mitodru Misra, Satyajit Halder, Puja Bag, Anirban Manna, Somesh Roy, Asanjan Brahmachari, Ankur...

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Selective PTP1B inhibition by A-1331852: Uncompetitive kinetics and...

Publication date: Available online 3 October 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Nathaly Vasquez-Martínez, Alejandro Sosa-Peinado, Francisco Cortés-Benítez, Martín González-Andrade

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Targeting the putative allosteric site J of cannabinoid receptor type 2 with...

Publication date: Available online 2 October 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Xinyi Zhang, Zhihui Chen, Mengxiang Su

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Pyridine-core scaffolds suppress A549 lung cancer cell progression:...

Publication date: Available online 1 October 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): K.B. Sachin Kumar, N.D. Satyanarayan, L. Vedavi, H. Vishwas, H.M. Kumaraswamy

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Neutral sphingomyelinase 2 inhibitors based on the...

Publication date: Available online 30 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Biswajit Kundu, Ajit G. Thomas, Matthew Stremlau, Ayush Bajaj, Louis Mueller, Arina Ranjit,...

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Synthesis of vincamine derivatives via Pictet-Spengler reaction leads to...

Publication date: Available online 30 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Christina Rodler, Dominik Wenisch, Zehra Özel, Michael Jakupec, Johann Schinnerl, Lothar Brecker

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Synthesis of axially chiral benzochalcogenophene derivatives and their...

Publication date: Available online 29 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Kanon Nakaie, Takumi Inoue, Rinko Mikyu, Nanami Otsuki, Eishi Ashihara, Takumi Furuta

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Hypoxia-activated 2-nitroimidazole-brusatol carbonate prodrugs for enhanced...

Publication date: Available online 28 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Jichong Li, Xuelan Ma, Zijian Liu, Xinyu Chang, Yifan Wei, Ning Ma, Xiaoling Liu, Xuan Zhang,...

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Criteria-guided selection of alternative zinc-binding groups of HDAC3...

Publication date: Available online 25 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Thabo Brighton Makgoba, Samuel Egieyeh, Erika Kapp, Jacques Joubert

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Rivastigmine-centered molecular hybridization strategies for multi-targeted...

Publication date: Available online 25 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Nitin Kumar, Virendra Kumar Kushwaha, Gourav Singh, Smriti Ojha, Alok Kumar Dash, Gauri Shankar

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Design, synthesis and biological evaluation of a series of new, potent FLT3...

Publication date: December 2026Source: Bioorganic & Medicinal Chemistry, Volume 143Author(s): Licheng Zhou, Yinglong Chen, Jiahe Li, Yayuan Yang, Wenyan Liu, Yingfan Liu, Bohai Fan, Yang Zhou,...

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Design, synthesis, and biological evaluation of novel dihydropyrimidinone...

Publication date: Available online 23 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Marian N. Gerges, Ahmed A. Noser, Eman G. Ibrahim, Thoria Diab

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Redirecting MurD inhibitor preference toward MurD2 through glutamate...

Publication date: Available online 15 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Zhuang Qian, Yu Nakashima, Tohru Dairi, Hiroyuki Morita

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Design, synthesis, biological and computational evaluation of Thieno[3,2-d]...

Publication date: Available online 12 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Poowadon Fukasem, Kittitat Jaengwang, Duangkamol Gleeson, Robert G. Britton, Kiattawee...

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An in vitro comparative study of cefiderocol, siderophore-aztreonam and...

Publication date: Available online 11 September 2026Source: Bioorganic & Medicinal ChemistryAuthor(s): Rui Liu, Patricia A. Miller, Marvin J. Miller

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Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1...

Publication date: December 2026Source: Bioorganic & Medicinal Chemistry, Volume 143Author(s): Ajay L. Chandgude, Giovanni Loriga, Andrea Beccu, Fabio Arturo Iannotti, Ester Pagano, Raffaele...

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Graphical abstract TOC

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Graphical abstract TOC

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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Contents continued

Publication date: November 2026Source: Bioorganic & Medicinal Chemistry, Volume 142Author(s):

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